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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b603f52d60d55bb0f30b49cb6bd33e70a86a2a23c6fb94c98d4a4a0d39be173' 
  AND token = 'zL0BTFWm3PIVlqeNeOWCKAgQbXjjZTNkhcpEjVBwK60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}