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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c1d29842967ba3ea80dc02c1706518898681e5d386ed41e32f441f8bfd8d86' 
  AND token = 'GMqWsm3Z0yx7Ju3Y6rJorMAEuQ1OcLzw6zYK1eovVcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}