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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3d75fab55e81d754e5ec82b5f2e48f3ddd8bd62e51afbfea1ef2a4346f9887' 
  AND token = 'tIF/39Y0Di78nJHRhTPLPDcWUiaknh0ImiL7380qtk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}