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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '441e8aca7dfbc796be90adbde3650e6f08d5d3a30bdf9c33fc2204c7a5ca1aae' 
  AND token = 'iHe1B+w5DltJcA5WxHO9Ei72vs2DNlb3PHTQd9M5VwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}