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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1bd1ac608ad1f93a147e6c2be2d847d7a53e209a56746b51d95ac5c3180323' 
  AND token = 'giysb/qkNi1lEXoxedx26IhHyr2EF8gH4H2NCwY11/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}