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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64163bf324d070ddc58a1e27f2afb9d1b6b9378a11900838a46bb556b515cd71' 
  AND token = '743DKi54Lwn7OcZhL2mV98SeWE1ylaG5YuhvNhXTQKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}