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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bf432586ae4c6e3b8381eb3069208b0e0849d2447073bf9b534d9a068001954' 
  AND token = 'ExvH24ZqMhHAX27POSY8xIu4fDsDc6OWheEYjWKnCd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}