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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2ee4e3bd21cf0f049dc0982cd5fdecafcda5da47434d99180b2c42b4610a04' 
  AND token = 'D5JoOjxU7iVDFj+YXQq2tkjVwUx06ZFXy0DFokvlvAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}