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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c49dbbd27e0544a88838b6c29c0e7c7826a87b2057d6c2bfd5f1a7771a18b5d' 
  AND token = '7xgSZc5/CFeMH9vP1uhYPv+sQAtEXVOl1h5Hf0dBRAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}