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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cacd4be105bd1b2e6623011a47eada2623bb07b7db2a950e151df863145cf0c' 
  AND token = 'SHPDnc7RchY8T6Mj4BU5Ui+G5WAcXFPFLaW2ZMFoq+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}