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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7521b12d171019eda736cb8d2a82217817f2b8c51d80e872be3b3df8c844c5f9' 
  AND token = '59YWEUhRRRZneSKif6cjM+gnbRcnBJX1ZTpjYvvAz3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}