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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65cde9c36ad74accfe9a2757bffd329e263b0f0473cc25a50bb6b05ddacb4c3' 
  AND token = 'S3HxERKv08g97hoWNMGab/b0/WhAZ0M8u4wfNvrghlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}