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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42b1826f860c8fdee4d4df749200262747e320d335f4275cbdd14ba902233b12' 
  AND token = 'E606IDesgxQkMYU894WJ9rraU17q6cAnYVKkIAA3Jw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}