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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f3839f6f3b28eb29b971e9c947d2bd4eaa1247fec944b11a4e0c646276e3eb2' 
  AND token = 'XB6QZ2PnytsXxhH/f5gTuXb2AsUKxS4ifGSptD+vhoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}