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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e431b89d18d9a4154450bbdd9875ceed5937426c55721d9a82f6142ef4c74e71' 
  AND token = 'amCEB4HwMUsTP2Hzlt7WXR6lZTdqz7kcp8FA91ji1Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}