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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e7b08ea801f8fb7e668f5026c721ffb73058f3e555cceec620225171a99219' 
  AND token = '1Geo7DfNFJz54cf9bZBNRDKDHnTWuQOE+B2DsE1CelI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}