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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db5fe3720a633fe1c177c1ce6e911df06e7c6e14880bbf274e2a84efda2ed134' 
  AND token = 'Jpz/mynYWb3Qi17FlHB4c2x2WwwkPd7diAl5HqPl5f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}