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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5bb461d2f4620f31f717099c9219605991a4ca7ee4878c6715bfca6486fb6b' 
  AND token = 'NGYGv3QJNPPLXqKi0HYccle8lNEaMSWfOZpBKFv3i4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}