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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e7918607bcbdf24a2443823f7cef6e012cfe830228f17c2188df57a863b1b7e' 
  AND token = 'Tg5Fc/o9Em7mz4aF+5rXSBEXRuCxyLa5BvTnjVPMEsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}