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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4500b3b8fab1faf2f19d7fd6aa5a47201f1af1c9649899cdb81afce75ba46a' 
  AND token = 'BN1/HHrDCgNkk8SzU4Gj/wbsrsVE1qpsO6bGxHd9REs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}