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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4976cfa3805bc6727a8470c767ce3062c042a6225444024b34d91e7360891620' 
  AND token = 'PFVwiYyuClsmf6ZydgtSuQfObW95K9XkVs6gn3hPX0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}