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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b0158f4ba5c618044ba617b55f3bbd6543468f1c762b43ae43cf135550cdba' 
  AND token = 'EcPSm8QKmCjDB5joGKXYF2t8glUi7OssF/KwAWDvtVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}