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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2cd80697f2604cab2880f8e9c30c972949bcaaeb87543aff0901c67a15cffbb' 
  AND token = 'T8wsL6RR7mcEs5YNiAhh7lTQqWB9S4hUfJ9PqB68goo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}