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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d867ad59d51d35783c629bc5b8a8a7fb4c5ba3e96710b275c86696a58a8a00' 
  AND token = 'N7NZpn1bWAD+S3bYYb5CicNzPzek+WH2qKBr1L9GJCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}