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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd00c6ca55c086587a9c8bf1162b5882ca0c9760d55c36162ffb82c1535a46165' 
  AND token = 'INwbx+H6x5XcdO41silYhwkcphIS4xxoR6HjpwdHK38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}