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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab6af28562df00c24567b6ca6d5b62f9fdd2c6983a4d58e1b91e3a07373fc390' 
  AND token = 'r9W9FPSHQRmsREPQmkSt2C+mUfPK23Nrc25DrJs9T4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}