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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a4814aa93fa540428ba28cebf99a3a2b3df2d1ea67d2a8a7fed1de391b72283' 
  AND token = 'MCmptsIfPKh0KZsJjB4wPjqr2t7l9XJ90fxLRPYWXjE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}