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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47b0cca65c3af5718b5da9f403452bb2c67ccb66e8ce27e1dd15f3bdc372c499' 
  AND token = 'IFoLymAa80xDXr0wrJrsHMGoagbVeD7ZKGOiJi2zFSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}