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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef202b0912be41b982d1fa7e3dffcf8152c6bf6421f8442151a4b07226277f4e' 
  AND token = 'ORl3Mzyf/Sq/vQpSTLZLSgK5mnt0DbFGEj5zsmFyC4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}