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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '47237f38289700016409e7dc0bed4715fe3a8294bf0e191d6fd44cd8b1227b89' 
  AND token = 'vuyG86JYDmunZE+rDFPjyWFn7Wvl29uNP0FppiAJy8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}