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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd60ec3f6e3e5db20daa34bdc525ada8405065ae1f574af5a7f16214017b59705' 
  AND token = 'RNNYS7Zr2tiGhba96UIWICUe6GDldmCOcUnj+BRwgCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}