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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88c0586ef0efd80bcd715affb81653f153f20f5d225661a7edd0fc554ddb290' 
  AND token = 'MD3BzWy0eAzdtfBa5r/N8849drCnH6oGbqkkhXRVsuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}