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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e1a59e752d6a1301013e66d4343c1375f2d45fc7f12247fd2c3fc2409cddb0' 
  AND token = 'Xk/CVEpJTXAGWbKKkQPple8XKheZemr5d64SVWB9RTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}