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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f91fe838d4f60b21fe2c79b9cbb0606420e4b5d52031f56a0c4e95efa49cd8b' 
  AND token = '27N96+zQz9y6jjpQ/urhRXSsRSJgTuihzGzSFthWmfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}