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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '453786ca12ea14ad0ea279acc7013c1f8cde7a1b2e8fa848b4b5b0c53a9c8301' 
  AND token = 'uvvzwXG8I4C5h9y1dQUAIXfROzZDYUucAdZqPxl5770=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}