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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79fe44f7be28b17f2736e1d9c31dc53a3390b48f6ba819b58695fd05c7ad2290' 
  AND token = 'y49JTSvh7MzOhz7TTD0rzwLmaCDUx8OzNxx2FrS1qW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}