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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7b16b90f07743efcf7fd84f0502adbc892cd850e93bc52b47f2bcf36d5afc42' 
  AND token = 'UJAprC+619nUiX08kl3RWvE7XaDvRxvkp7x0cL6Gh6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}