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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c197d545ceddfecbd8ca67ae12a9fc487e2e4aacc3bc2608506e0d8f4c9b3dc' 
  AND token = 'HIXQM8c2o1lpGPBM4m8MlmbVJvdjwzlrNNPtBu0bGSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}