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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8c00bd2bea0c228e888023c0cecaf199590eb1375e1c65a01e515aaf5b409db' 
  AND token = '15UoWKZ56ml982hRgcVgq4dgh0D/GOeJt2T7o8M7HsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}