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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12deefcf901dfabff10de19110c8ce2d21ea2f25c9ef7f79e17d95da2a5f5eb8' 
  AND token = 'x/6Acx0K9A7MGpBxEmlIwgNLac4g2rFfuNdFtJlWXOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}