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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '768f1f50294ece917a9aea8008cd05f0b63d8d083e173a4a40eeccd5a68b59be' 
  AND token = 'Pm2nQ6olAcQ46tStepEy2BXlwJCQXFC5AiAIDqzcKI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}