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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5188eab7cffae0a7859f12516540da0ff0148731e2fa6310f4f41ad2eb4059d' 
  AND token = 'hBmqr9Rld6mxqQcJMuGB2vlc4H5Y96/HCLtZAWcw1dk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}