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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5da73c8557e9dcdff77069d2f50fdcdd86fa2c7fa6c656cac03d39c93ec1cd22' 
  AND token = 'O6t6z/Z05QbZ4gwd7OT5giJLhEY4SeTTmIfUVz9wf5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}