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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fd1b49eacef39b5137d24b061e9e8815d8235d3abbc5c15680a7d0729c8d44f' 
  AND token = 'm1fl09lqcUJV8C8oDUDPXaLglzqm5nfse0LXEIRGkeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}