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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef5aa78f1b3b511c3f22f9f2e9b9b61aaa8ce9a404d97bde4b00e1e6d7881cc' 
  AND token = 'qZ7N7zEjJACXsNh+D5r3DgfMyhOWup+VOjhxAeVDlsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}