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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9105677f91bbfc18e0325c36f4b8263dd634c818333f6e14589117ee5c99cb' 
  AND token = 'jIA7FHMUaBbOLaoWg8T5KTlFMy6WRc4wzKMY6sha5R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}