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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fb4a46e0c68cae863a4ce6c7dc3812351c2fbd4a455e24dcfe5735d4a077371' 
  AND token = 'n782/oZUdme4IARbe6cUegVQGprA8sBOX5BNl9vsHqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}