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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d4f2ff4c164059352053177fc92f80b95b2ef6ebd01af14dd334295a88c183' 
  AND token = 'OIx1ACAEz1HAB1bhWDFU2vsTJhGfNBcbamx46s8eELk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}