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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50abf8ba41871af505f99a93c61dddb2907d20d0a2d8e26015c0fe99b40d6bb' 
  AND token = '2CRAelwOXAU/h8GM8YCsp7Sikl/8z4NFH+tDZt3InuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}