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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6fa1dc5d436bdf9d8d52ea429a27648584467c27417f4a867382e26226c429' 
  AND token = 'JhlOz6SyJOikryDdW8O1Mj0gd4q465WqZpaTJtSfpiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}